A substance most possess the following three characteristics to be immunologic. 1) Foreignness 2) High Molecular weight 3) Chemical Complexity 4) Solubility (biodegradability)1) Foreignness:Animals normally do not respond immunologically to “self”, for example, if a RABBIT is injected with its own serum albumin, it will not mount an immune response. It recognizes the albumin as self. In contrast, if rabbit serum albumin as “foreign” and mount an immune response against it. To prove that the rabbit, which did not respond to its own serum albumin because it recognizes the substance as foreign. Thus, the first requirement for a compound to be immunogenic is foreignness. The substance as foreign. Thus, the first requirement for a compound to be immunogenic is foreignness. The more foreign the substance the more immunogenic it is. 2) High Molecular Weight:Compounds that have a molecular weight of less than 1000 daltons are not immunogenic (e.g: Penicillin, Progesterone, Aspirin) Compou…